After World War II, the US Air Force stored this C-46 in 1946. Sold to Flying Tiger Line in 1950, the Commando flew passengers and freight for the next 38 years. In 1988, however, the aircraft was seized by US Marshalls for allegedly running guns. It was later turned over to the Smithsonian Institution and placed on permanent loan to the National Warplane Museum. On loan to the Glen H Curtiss Museum since around 2001, it's located at the entrance to the museum in Hammondsport, NY.

Operated by the Geisinger Health System in central, south-central and northeastern Pennsylvania and southern New Jersey.

Calspan Corporation's Flight Research division Strike Saab works for the Naval Air Warfare Command testing and training in the (ASTARS II (Airborne Systems Training and Research Support) program.

Used by U2 for their 2018 tour.